Dedicator of Cytokinesis 3 (DOCK3) Antibody (HRP)
Pida mas información
935106861
info@markelab.com
Precio
169€ (20 µg)
Antibody anti-DOCK3
proveedor
Abbexareference
abx313604Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
PolyclonalDescripción
DOCK3 Antibody (HRP) is a Rabbit Polyclonal against DOCK3 conjugated to HRP.
Background
DOCK3, or MOCA, is a neuron-specific GEF for Rac1 that regulates neurite outgrowth, axonal growth, and synaptic plasticity in the CNS. It mediates actin rearrangement, promoting axonal guidance and dendritic remodeling. Highly expressed in neurons, DOCK3 maintains synapse connectivity and supports neuroprotection. Dysregulation contributes to neurodegenerative diseases like Alzheimer’s, where it influences tau phosphorylation and cell survival pathways such as ERK/Akt activation. DOCK3 deficiency causes motor and cognitive impairments in mouse models, highlighting its role in neuronal development, CNS recovery, and axonal regeneration.
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human
immunogen target
Dedicator of Cytokinesis 3 (DOCK3)
host
Rabbit
isotype
IgG
conjugation
HRP
form
Liquid
tested applications
ELISA
purity
> 95%
purification
Purified by Protein G.
recommended dilution
Optimal dilutions/concentrations should be determined by the end user.
buffer
0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.
size 1
20 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
1 mg
storage
Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles.
or code
DOCK3
dry ice
No
availability
Shipped within 5-10 working days.
alias
DOCK3, MOCA, PBP, Dock3, dedicator of cytokinesis 3, NEDIDHA
uniprot id
Quizá le pueda interesar
anti- DOCK3; MOCA antibody
proveedor
FineTestreference
FNab02494Tested Applications
ELISA, WBreactivity
human,mousestatus
RUOclonality
polyclonalPrecio a consultar
Ver másDedicator of Cytokinesis 3 (DOCK3) Antibody
proveedor
Abbexareference
abx112011Tested Applications
ELISA, WBreactivity
Human, Mousestatus
RUOclonality
PolyclonalDedicator Of Cytokinesis 3 Antibody is a Rabbit Polyclonal antibody against Dedicator Of Cytokinesis 3.
637€ (100 µl)
Ver másHuman Dedicator Of Cytokinesis 3 (DOCK3) ELISA Kit
proveedor
Abbexareference
abx151335Tested Applications
ELISAreactivity
Humanstatus
RUOHuman Dedicator Of Cytokinesis 3 (DOCK3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human De...
715€ (96 tests)
Ver más