DCC-Interacting Protein 13-Beta (APPL2) Antibody
169€ (20 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
DCC-Interacting Protein 13-Beta (APPL2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx340836
tested applications
ELISA, IHC, IF/ICC
Description
DCC-Interacting Protein 13-Beta (APPL2) Antibody is a Rabbit Polyclonal antibody for the detection of Human APPL2.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | DCC-Interacting Protein 13-Beta (APPL2) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G chromatography. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA, IHC, IF/ICC |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q8NEU8 |
| Alias | DIP13B,Dip13-beta,Adapter protein containing PH domain, PTB domain and leucine zipper motif 2 |
| Background | Antibody anti-APPL2 |
| Status | RUO |
Descripción
APPL2 (Phosphotyrosine Interacting with PH Domain and Leucine Zipper 2) is another member of the APPL protein family, similar to APPL1. Like APPL1, APPL2 also contains a pleckstrin homology (PH) domain and a leucine zipper, enabling it to interact with phosphotyrosine-containing proteins. APPL2 is involved in a wide range of cellular processes including endocytosis, signal transduction, and the regulation of vesicular trafficking. It is particularly important in regulating the function of the insulin receptor and in modulating signaling pathways that control cell growth, survival, and metabolism. APPL2 is known to affect cellular responses to growth factors and contributes to the regulation of neuronal function and plasticity. Its role in intracellular signaling makes it a relevant protein in understanding diseases like diabetes and neurodegenerative conditions.
Related Products
Human APPL2(DCC-Interacting Protein 13-Beta) ELISA Kit
Ver Producto
anti- APPL2 antibody
Required for the regulation of cell proliferation in response to extracellular signals mediated by an early endosomal compartment. Links Rab5 to nuclear signal transduction.
Ver Producto