Cytosolic Carboxypeptidase 2 (AGBL2) Antibody (Biotin)
169€ (20 µg)
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name
Cytosolic Carboxypeptidase 2 (AGBL2) Antibody (Biotin)
category
Primary Antibodies
provider
Abbexa
reference
abx307713
tested applications
ELISA
Description
AGBL2 Antibody (Biotin) is a Rabbit Polyclonal against AGBL2 conjugated to Biotin.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Cytosolic Carboxypeptidase 2 (AGBL2) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Biotin |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q5U5Z8 |
| Gene ID | 79841 |
| NCBI Accession | NP_079059.2, NM_024783.3 |
| OMIM | 617345 |
| Alias | CCP2 |
| Background | Antibody anti-AGBL2 |
| Status | RUO |
Descripción
AGBL2 is another tubulin-modifying enzyme that regulates microtubule stability by cleaving polyglutamate chains from tubulin. It is expressed in various tissues, including the brain, where it contributes to neuronal function, axonal transport, and synaptic organization. AGBL2 plays a role in neurodegenerative diseases, with studies linking its dysregulation to tauopathies, including Alzheimer's disease, where abnormal polyglutamylation of microtubules contributes to neuronal dysfunction. In addition to its neural roles, AGBL2 has been implicated in cancer, where it modulates cell division and migration through its influence on the cytoskeleton.
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