Cytosolic Carboxypeptidase 2 (AGBL2) Antibody
221€ (50 µg)
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935106861
info@markelab.com
name
Cytosolic Carboxypeptidase 2 (AGBL2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx325922
tested applications
ELISA, WB, IHC
Description
AGBL2 Antibody is a Rabbit Polyclonal against AGBL2.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Cytosolic Carboxypeptidase 2 (AGBL2) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | ELISA: 1/40000, WB: 1/500 - 1/2000, IHC: 1/100 - 1/300. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q5U5Z8 |
| Gene ID | 79841 |
| Alias | CCP2 |
| Background | Antibody anti-AGBL2 |
| Status | RUO |
Descripción
AGBL2 is another tubulin-modifying enzyme that regulates microtubule stability by cleaving polyglutamate chains from tubulin. It is expressed in various tissues, including the brain, where it contributes to neuronal function, axonal transport, and synaptic organization. AGBL2 plays a role in neurodegenerative diseases, with studies linking its dysregulation to tauopathies, including Alzheimer's disease, where abnormal polyglutamylation of microtubules contributes to neuronal dysfunction. In addition to its neural roles, AGBL2 has been implicated in cancer, where it modulates cell division and migration through its influence on the cytoskeleton.
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