Cyclin-Dependent Kinase 4 (CDK4) Antibody
338€ (60 µl)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Cyclin-Dependent Kinase 4 (CDK4) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx000696
Tested Applications
WB, IHC, IP
Description
CDK4 Antibody is a Rabbit Polyclonal antibody against CDK4. The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a). This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb). Mutations in this gene as well as in its related proteins including D-type cyclins, p16(INK4a) and Rb were all found to be associated with tumorigenesis of a variety of cancers. Multiple polyadenylation sites of this gene have been reported.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Cyclin-Dependent Kinase 4 (CDK4) Immunogen: A synthetic peptide corresponding to human CDK4 |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Assay Type | Concentration: 1 mg/ml |
| Recommended Dilution | WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200, IP: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Calculated MW: 20 kDa/33 kDa Observed MW: 30 kDa |
| Purification | Purified by affinity chromatography. |
| Size 1 | 60 µl |
| Size 2 | 120 µl |
| Size 3 | 200 µl |
| Form | Liquid |
| Tested Applications | WB, IHC, IP |
| Buffer | PBS, pH 7.3, containing 0.01% thiomersal, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P11802 |
| Gene ID | 1019 |
| NCBI Accession | NP_000066.1 |
| Background | Antibody anti-CDK4 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Productos relacionados
Cyclin-Dependent Kinase 4 (CDK4) Antibody
CDK4 Antibody is a Rabbit Polyclonal antibody against CDK4. The protein encoded by this gene is a member of the Ser/Thr …
Ver producto
Cyclin-Dependent Kinase 4 (CDK4) Antibody
CDK4 is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevis…
Ver producto