Cyclic ADP Ribose Hydrolase (CD38) Antibody (PE)

Este producto es parte de CD38 - CD38 molecule
Cyclic ADP Ribose Hydrolase (CD38) Antibody (PE)
533€ (100 tests)

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Name
Cyclic ADP Ribose Hydrolase (CD38) Antibody (PE)
Category
Primary Antibodies
Provider
Abbexa
Reference
abx412644
Tested Applications
FCM

Description

Cyclic ADP Ribose Hydrolase (CD38) Antibody (PE) is a Mouse Monoclonal antibody against Cyclic ADP Ribose Hydrolase (CD38).

Documentos del producto

Instrucciones
Data sheet
Descargar

Especificaciones del producto

Category
Primary Antibodies
Immunogen Target
Target: Cyclic ADP Ribose Hydrolase (CD38)
Host
Mouse
Reactivity
Human
Detection Method
Laser Line: 550
Excitation/Emission: 565/575
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Clonality
Monoclonal
Conjugation
PE
Isotype
IgG1
Purification
Purified
Size 1
100 tests
Form
Lyophilized
Tested Applications
FCM
Buffer
PBS, 1% BSA. Contains sodium azide.
Availability
Shipped within 3-7 working days.
Storage
Store at -20°C or -80°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P28907
Alias
ADPRC1,Cadpr1,ADPRC 1,ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1,2'-phospho-ADP-ribosyl cyclase,2'-phospho-cyclic-ADP-ribose transferase,ADP-ribosyl cyclase 1,Cyclic ADP-ribose hydrolase 1
Background
Antibody anti-CD38
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

Background

CD38 is a multifunctional membrane glycoprotein expressed on a variety of cells, including immune cells (B cells, T cells, monocytes, and natural killer cells), as well as non-hematopoietic cells like those in the pancreas, brain, and muscle. Initially identified as a cell-surface receptor on lymphocytes, CD38 has since been recognized for its roles in enzyme-mediated metabolism, cell adhesion, and signal transduction. This protein is particularly well-known for its enzymatic activity in catalyzing the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD+, which serves as an important second messenger in calcium signaling pathways. CD38 plays crucial roles in the regulation of intracellular calcium levels, influencing processes such as cell activation, proliferation, and differentiation.

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