Cyclic ADP-Ribose Hydrolase 2 (BST1) Antibody

Product specifications

Primary Antibodies

Cyclic ADP-Ribose Hydrolase 2 (BST1)

Rabbit

Mouse

WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user.

Polyclonal

Unconjugated

Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography.

100 µl

200 µl

1 ml

Liquid

WB, IHC, IF/ICC

0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol.

Shipped within 5-7 working days.

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

No

ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2,ADP-ribosyl cyclase 2,CD157,Cadpr2,Bone marrow stromal cell antigen 1,Cyclic ADP-ribose hydrolase 2

Antibody anti-BST1

RUO

Descripción

BST1, also known as bone marrow stromal cell antigen 1 or CD157, is a multifunctional glycoprotein involved in immune signaling, cell adhesion, and calcium signaling. BST1 is part of the ADP-ribosyl cyclase family, which also includes CD38, another NAD-glycohydrolase enzyme involved in immune and calcium signaling. It is encoded by the BST1 gene located on chromosome 4p15 in humans and is predominantly expressed in bone marrow stromal cells, but also in peripheral immune cells, endothelial cells, and various tissues with immune functions. BST1 is also identified as a GPI (glycosylphosphatidylinositol)-anchored protein, which enables it to be tethered to cell membranes, facilitating cell-cell interactions and intracellular signaling. This protein is highly relevant in immunology, given its involvement in cellular processes associated with immune responses and inflammation.

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