Cyclic ADP-Ribose Hydrolase 2 (BST1) Antibody
52€ (10 µg)
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Name
Cyclic ADP-Ribose Hydrolase 2 (BST1) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx014158
Tested Applications
ELISA, WB
Description
Rabbit polyclonal antibody against BST1 protein. Immunogen region is Internal.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Cyclic ADP-Ribose Hydrolase 2 (BST1) Immunogen: The antiserum was produced against synthesized peptide derived from internal of human BST1. |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Assay Type | Concentration: 1 mg/ml |
| Recommended Dilution | WB: 1/500 - 1/3000, ELISA: 1/5000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. |
| Size 1 | 10 µg |
| Size 2 | 100 µg |
| Size 3 | 200 µg |
| Size 4 | 300 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS (without Mg<sup>2+</sup> and Ca<sup>2+</sup>), pH 7.4, 150 mM NaCl, 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q10588 |
| Alias | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2,ADP-ribosyl cyclase 2,CD157,Cadpr2,Bone marrow stromal cell antigen 1,Cyclic ADP-ribose hydrolase 2 |
| Background | Antibody anti-BST1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
BST1, also known as bone marrow stromal cell antigen 1 or CD157, is a multifunctional glycoprotein involved in immune signaling, cell adhesion, and calcium signaling. BST1 is part of the ADP-ribosyl cyclase family, which also includes CD38, another NAD-glycohydrolase enzyme involved in immune and calcium signaling. It is encoded by the BST1 gene located on chromosome 4p15 in humans and is predominantly expressed in bone marrow stromal cells, but also in peripheral immune cells, endothelial cells, and various tissues with immune functions. BST1 is also identified as a GPI (glycosylphosphatidylinositol)-anchored protein, which enables it to be tethered to cell membranes, facilitating cell-cell interactions and intracellular signaling. This protein is highly relevant in immunology, given its involvement in cellular processes associated with immune responses and inflammation.
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