CUB Domain-Containing Protein 1 (CDCP1) Antibody (FITC)

Este producto es parte de CDCP1 - CUB domain containing protein 1
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364€ (0.1 mg)

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935106861
info@markelab.com
name
CUB Domain-Containing Protein 1 (CDCP1) Antibody (FITC)
category
Primary Antibodies
provider
Abbexa
reference
abx140650
tested applications
FCM

Description

CUB Domain-Containing Protein 1 (CDCP1) Antibody is a Mouse Monoclonal CUB Domain-Containing Protein 1 (CDCP1).

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
CUB Domain-Containing Protein 1 (CDCP1)
Host
Mouse
Reactivity
Human
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Clonality
Monoclonal
Conjugation
FITC
Isotype
IgG2b
Clone ID
J391
Size 1
0.1 mg
Tested Applications
FCM
Buffer
PBS solution with 15 mM sodium azide.
Availability
Shipped within 5-12 working days.
Storage
Store in the dark at 2-8°C. Avoid exposure to light. Do not freeze.
Dry Ice
No
UniProt ID
Q9H5V8
Gene ID
64866
Alias
Membrane glycoprotein gp140,CD318,TRASK,SIMA135,Subtractive immunization M plus HEp3-associated 135 kDa protein
Background
Antibody anti-CDCP1
Status
RUO
Note
Concentration: 0.1 mg/ml - 

Descripción

CDCP1 (CUB Domain Containing Protein 1), also known as CD318 or Trask, is a transmembrane protein widely expressed across cell types, including epithelial cells, stem cells, and notably in certain types of cancer cells. CDCP1 is known for its involvement in various cellular processes, including cell adhesion, migration, and signal transduction. It is a single-pass membrane protein characterized by extracellular CUB domains, which are implicated in protein-protein interactions, especially in cell communication and adhesion mechanisms. CDCP1 plays a crucial role in cancer biology, as its overexpression or aberrant activation has been observed in multiple malignancies, such as lung, colon, and breast cancer, where it contributes to processes like invasion, metastasis, and resistance to apoptosis. This makes CDCP1 an important molecule in cancer progression and a potential target for therapeutic interventions. Moreover, CDCP1 is implicated in non-cancerous biological pathways, including wound healing and tissue remodeling, which involve dynamic changes in cell adhesion and migration.

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