CUB Domain-Containing Protein 1 (CDCP1) Antibody (APC)
429€ (100 tests)
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935106861
info@markelab.com
name
CUB Domain-Containing Protein 1 (CDCP1) Antibody (APC)
category
Primary Antibodies
provider
Abbexa
reference
abx140642
tested applications
FCM
Description
CUB Domain-Containing Protein 1 (CDCP1) Antibody (APC) is a mouse monoclonal antibody against CUB Domain-Containing Protein 1 (CDCP1).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | CUB Domain-Containing Protein 1 (CDCP1) |
| Host | Mouse |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | APC |
| Isotype | IgG2b |
| Clone ID | J391 |
| Purification | The purified antibody is conjugated with allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography. |
| Size 1 | 100 tests |
| Tested Applications | FCM |
| Buffer | Stabilizing PBS solution containing 15 mM sodium azide. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store in the dark at 2-8°C. Avoid exposure to light. Do not freeze. |
| Dry Ice | No |
| UniProt ID | Q9H5V8 |
| Gene ID | 64866 |
| Alias | Membrane glycoprotein gp140,CD318,TRASK,SIMA135,Subtractive immunization M plus HEp3-associated 135 kDa protein |
| Background | Antibody anti-CDCP1 |
| Status | RUO |
Descripción
CDCP1 (CUB Domain Containing Protein 1), also known as CD318 or Trask, is a transmembrane protein widely expressed across cell types, including epithelial cells, stem cells, and notably in certain types of cancer cells. CDCP1 is known for its involvement in various cellular processes, including cell adhesion, migration, and signal transduction. It is a single-pass membrane protein characterized by extracellular CUB domains, which are implicated in protein-protein interactions, especially in cell communication and adhesion mechanisms. CDCP1 plays a crucial role in cancer biology, as its overexpression or aberrant activation has been observed in multiple malignancies, such as lung, colon, and breast cancer, where it contributes to processes like invasion, metastasis, and resistance to apoptosis. This makes CDCP1 an important molecule in cancer progression and a potential target for therapeutic interventions. Moreover, CDCP1 is implicated in non-cancerous biological pathways, including wound healing and tissue remodeling, which involve dynamic changes in cell adhesion and migration.
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