Crk Like Protein (CRKL) Antibody
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935106861
info@markelab.com
Precio
416€ (200 µl)
Antibody anti-CRKL
proveedor
Abbexareference
abx432554Tested Applications
P-ELISA, WB, IHCreactivity
Humanstatus
RUOclonality
PolyclonalDescripción
CRKL Antibody is a Goat Polyclonal antibody against CRKL.
Background
Crk-like protein (CRKL) is another adaptor protein that is structurally similar to CRK but has its own unique functions in cellular signaling. Like CRK, CRKL contains SH2 and SH3 domains, enabling it to interact with a variety of signaling molecules involved in cellular growth, survival, and migration. CRKL is a key component of signaling pathways activated by various RTKs, including those involved in cell differentiation and cytoskeletal remodeling. It plays an important role in cellular responses to growth factors, such as epidermal growth factor (EGF), and is implicated in the regulation of immune cell function. Dysregulation of CRKL has been linked to certain cancers and other diseases where altered cellular signaling occurs.
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human
immunogen target
Crk Like Protein (CRKL)
host
Goat
isotype
IgG
conjugation
Unconjugated
form
Liquid
tested applications
P-ELISA, WB, IHC
purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
recommended dilution
P-ELISA: 1/16000. Optimal dilutions/concentrations should be determined by the end user.
buffer
Tris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin.
size 1
200 µl
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
CRKL
dry ice
No
availability
Shipped within 5-10 working days.
alias
CRK like proto-oncogene, crk-like protein
NCBI accession
NP_005198.1
note
Concentration: 0.5 mg/ml -
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
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