CREB Regulated Transcription Coactivator 3 (CRTC3) Antibody

Descripción

Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites.Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation.Enhances the interaction of CREB1 with TAF4.Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR.Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells.Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR).Tissue specificity: Predominantly expressed in B and T lymphocytes.Highest levels in lung.Also expressed in brain, colon, heart, kidney, ovary, and prostate.Weak expression in liver, pancreas, muscle, small intestine, spleen and stomach.

Características del producto

clonality

Monoclonal

reactivity

Human, Monkey

immunogen target

CREB Regulated Transcription Coactivator 3 (CRTC3)

host

Mouse

conjugation

Unconjugated

form

Liquid

tested applications

ELISA, WB, IHC, IF/ICC

purification

Unpurified ascites.

buffer

Ascitic fluid containing 0.03% sodium azide.

size 1

100 µl

storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

or code

CRTC3

dry ice

availability

Shipped within 5-10 working days.

gene id

https://www.ncbi.nlm.nih.gov/gene/64784

note

This product is for research use only.

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