Creatine Kinase U-Type, Mitochondrial (CKMT1) Antibody
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
Mitochondrial creatine kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase, this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80% homology with the coding exons of sarcomeric mitochondrial creatine kinase.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Creatine Kinase U-Type, Mitochondrial (CKMT1) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P12532 |
| Gene ID | 1159, 548596 |
| OMIM | 123290 |
| Background | Antibody anti-CKMT1 |
| Status | RUO |
Descripción
Related Products
Creatine Kinase U-Type, Mitochondrial (CKMT1) Antibody
Mitochondrial creatine kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase, this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80% homology with the coding exons of sarcomeric mitochondrial creatine kinase.
Ver Producto
Mouse Creatine Kinase U-Type, Mitochondrial (CKMT1) CLIA Kit
Mouse Creatine Kinase U-Type, Mitochondrial (CKMT1) Chemiluminescent Immunoassay (CLIA) Kit is a Chemiluminescent Immunoassay (CLIA) kit against Creatine Kinase U-Type, Mitochondrial (CKMT1).
Ver Producto
Mouse Creatine Kinase U-Type, Mitochondrial (CKMT1) ELISA Kit
Mouse Creatine Kinase U-Type, Mitochondrial (CKMT1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Creatine Kinase U-Type, Mitochondrial (CKMT1) concentrations in tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.
Ver Producto