Cow Vascular Endothelial Growth Factor A (VEGFA) Protein
351€ (5 µg)
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Name
Cow Vascular Endothelial Growth Factor A (VEGFA) Protein
Category
Proteins and Peptides
Provider
Abbexa
Reference
abx670136
Tested Applications
ELISA
Description
Cow Vascular Endothelial Growth Factor A (VEGFA) Protein is a Recombinant protein expressed in Pichia pastoris.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Proteins and Peptides |
| Immunogen Target | Vascular Endothelial Growth Factor A (VEGFA) |
| Host | Yeast |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Origin | Cow |
| Conjugation | Unconjugated |
| Size 1 | 5 µg |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Buffer | Prior to lyophilization: Phosphate buffered saline |
| Availability | Shipped within 3-7 working days. |
| Storage | Store at 4°C for up to one week. For long-term storage, store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P15691 |
| Alias | L-VEGF,MVCD1,VEGF,VPF,Vascular permeability factor |
| Background | Protein VEGFA |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
VEGFA is a key member of the vascular endothelial growth factor (VEGF) family and plays a crucial role in angiogenesis, vascular permeability, and endothelial cell proliferation VEGFA binds primarily to its receptors VEGFR-1 and VEGFR-2, triggering signaling pathways like PI3K/AKT and ERK/MAPK to promote blood vessel formation during embryonic development, wound healing, and tissue repair Dysregulated VEGFA expression is associated with pathological angiogenesis observed in cancer, diabetic retinopathy, and age-related macular degeneration (AMD) VEGFA also increases vascular permeability by altering endothelial junctions, contributing to fluid leakage in conditions such as inflammation and tumors Targeted therapies, such as bevacizumab and other anti-VEGF agents, inhibit VEGFA activity to suppress angiogenesis and tumor growth in various cancers and ocular diseases
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