Cow Lysophosphatidic Acid Receptor 1 (LPAR1) ELISA Kit

Pida mas información
935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for LPAR1
proveedor
Abbexareference
abx521311Tested Applications
ELISAreactivity
Cowstatus
RUOclonality
Descripción
Cow Lysophosphatidic Acid Receptor 1 (LPAR1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Cow Lysophosphatidic acid receptor 1 concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
LPAR1 is a G protein-coupled receptor activated by lysophosphatidic acid (LPA), a bioactive phospholipid involved in diverse cellular processes. LPAR1 is widely expressed in various tissues, including the brain, lungs, and fibroblasts, where it mediates cell proliferation, survival, migration, and cytoskeletal reorganization. LPAR1 couples to multiple G proteins (Gi, Gq, and G12/13), activating pathways such as MAPK, Rho/ROCK, and PI3K/Akt. In fibrosis, LPAR1 signaling promotes fibroblast activation and extracellular matrix deposition, contributing to pulmonary, hepatic, and renal fibrosis. It is also implicated in neuropathic pain, where LPAR1 activation sensitizes pain pathways and amplifies neuronal signaling. In cancer, LPAR1 drives tumor growth, metastasis, and angiogenesis, particularly in breast and lung cancers. Dysregulation of LPAR1 is associated with inflammatory disorders, cancer progression, and fibrosis. LPAR1 antagonists are being developed as potential therapies for fibrotic diseases, neuropathic pain, and cancer, highlighting its role as a key modulator of cell migration and tissue remodeling.
Características del producto
category
ELISA Kits
immunogen target
Lysophosphatidic Acid Receptor 1 (LPAR1)
reactivity
Cow
test range
0.156 ng/ml - 10 ng/ml
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
LPAR1,EDG2,LPA1,VZG1,edg-2,vzg-1,Gpcr26,Mrec1.3,rec.1.3,GPR26,endothelial differentiation gene 2,lysophosphatidic acid G-protein-coupled receptor, 2,LPA receptor 1,lysophosphatidic acid receptor Edg-2
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
LPAR1
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
Quizá le pueda interesar
Human LPAR1(Lysophosphatidic acid receptor 1) ELISA Kit

proveedor
FineTestreference
EH2508reactivity
humanstatus
RUOPrecio a consultar
Ver másLPA Receptor 1 Antibody

proveedor
Abbexareference
abx019130Tested Applications
WBreactivity
Mousestatus
RUOclonality
PolyclonalLPA Receptor 1 Antibody is a Rabbit Polyclonal antibody against Mouse.
312€ (100 µg)
Ver másHuman Lysophosphatidic Acid Receptor 1 (LPAR1) ELISA Kit

proveedor
Abbexareference
abx152223Tested Applications
ELISAreactivity
Humanstatus
RUOHuman Lysophosphatidic Acid Receptor 1 (LPAR1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Hu...
715€ (96 tests)
Ver más