Cow Fc Fragment of IgG, Low Affinity IIb, Receptor (CD32) (FCGR2B) ELISA Kit
Pida mas información
935106861
info@markelab.com
Precio
687.5€ (96 tests)
Elisa Kits FCGR2B
proveedor
Abbexareference
abx517840Tested Applications
ELISAreactivity
Cowstatus
RUOclonality
Descripción
Cow Fc Fragment of IgG, Low Affinity IIb, Receptor (CD32) (FCGR2B) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Cow Fc Fragment of IgG, Low Affinity IIb, Receptor (CD32) (FCGR2B) concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
FCGR2B (Fc gamma receptor IIB), also known as CD32B, is a low-affinity receptor for the Fc portion of IgG antibodies, primarily responsible for regulating immune responses by mediating inhibitory signaling. It plays a crucial role in the balance between activation and inhibition of immune cells, preventing excessive inflammation and autoimmunity. Unlike its closely related receptor, FCGR2A, which triggers activating signals, FCGR2B is the only inhibitory receptor within the Fc gamma receptor family. This receptor is predominantly expressed on B cells, dendritic cells, macrophages, and other immune cells. FCGR2B is part of the larger family of Fc gamma receptors (FcγRs), which bind the Fc region of immunoglobulin G (IgG) to mediate immune responses such as phagocytosis, cytokine release, and the clearance of immune complexes. Its inhibitory role is vital in the prevention of autoimmune reactions and the modulation of inflammatory responses.
Características del producto
category
ELISA Kits
immunogen target
Fc Fragment of IgG, Low Affinity IIb, Receptor (CD32) (FCGR2B)
reactivity
Cow
test range
0.312 ng/ml - 20 ng/ml
assay data
Quantitative
detection method
Colorimetric
sample type
Tissue homogenates,Cell lysates,Other biological fluids
size 1
96 tests
alias
CD32,FCG2,CD32B,FCGR2,IGFR2,FCGR2C,FcGRIIB,FcRII-c,FcgammaRIIb,Low affinity immunoglobulin gamma Fc region receptor II-b,IgG Fc receptor II-b,CDw32,Fc-gamma RII-b
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
FCGR2B
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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