Cow Fc Fragment of IgG, Low Affinity IIb, Receptor (CD32) (FCGR2B) ELISA Kit

Este producto es parte de FCGR2B - Fc gamma receptor Iib
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715€ (96 tests)

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935106861
info@markelab.com
name
Cow Fc Fragment of IgG, Low Affinity IIb, Receptor (CD32) (FCGR2B) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx517840
tested applications
ELISA

Description

Cow Fc Fragment of IgG, Low Affinity IIb, Receptor (CD32) (FCGR2B) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Cow Fc Fragment of IgG, Low Affinity IIb, Receptor (CD32) (FCGR2B) concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
ELISA Kits
Immunogen Target
Fc Fragment of IgG, Low Affinity IIb, Receptor (CD32) (FCGR2B)
Reactivity
Cow
Detection Method
Colorimetric
Assay Data
Quantitative
Test Range
0.312 ng/ml - 20 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-12 working days. The validity for this kit is 6 months.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
Q28110
Alias
CD32,FCG2,CD32B,FCGR2,IGFR2,FCGR2C,FcGRIIB,FcRII-c,FcgammaRIIb,Low affinity immunoglobulin gamma Fc region receptor II-b,IgG Fc receptor II-b,CDw32,Fc-gamma RII-b
Background
Elisa kits for FCGR2B
Status
RUO
Note
Validity: The validity for this kit is 6 months.
This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

FCGR2B (Fc gamma receptor IIB), also known as CD32B, is a low-affinity receptor for the Fc portion of IgG antibodies, primarily responsible for regulating immune responses by mediating inhibitory signaling. It plays a crucial role in the balance between activation and inhibition of immune cells, preventing excessive inflammation and autoimmunity. Unlike its closely related receptor, FCGR2A, which triggers activating signals, FCGR2B is the only inhibitory receptor within the Fc gamma receptor family. This receptor is predominantly expressed on B cells, dendritic cells, macrophages, and other immune cells. FCGR2B is part of the larger family of Fc gamma receptors (FcγRs), which bind the Fc region of immunoglobulin G (IgG) to mediate immune responses such as phagocytosis, cytokine release, and the clearance of immune complexes. Its inhibitory role is vital in the prevention of autoimmune reactions and the modulation of inflammatory responses.

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