Cow Ectonucleoside Triphosphate Diphosphohydrolase 1 (ENTPD1) ELISA Kit
715€ (96 tests)
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Name
Cow Ectonucleoside Triphosphate Diphosphohydrolase 1 (ENTPD1) ELISA Kit
Category
ELISA Kits
Provider
Abbexa
Reference
abx520960
Tested Applications
ELISA
Description
Cow Ectonucleoside Triphosphate Diphosphohydrolase 1 (ENTPD1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Cow Ectonucleoside Triphosphate Diphosphohydrolase 1 (ENTPD1) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | ELISA Kits |
| Immunogen Target | Ectonucleoside Triphosphate Diphosphohydrolase 1 (ENTPD1) |
| Reactivity | Cow |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Standard Form: Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-12 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | O18956 |
| Alias | CD39,SPG64,ATP-DPH,ATPDase,NTPDase-1,ATP diphosphohydrolase,Ecto-ATP diphosphohydrolase 1,Ecto-apyrase,Lymphoid cell activation antigen ,Nucleoside triphosphate diphosphohydrolase 1 |
| Background | Elisa Kits for: ENTPD1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout. |
Background
ENTPD1, also known as CD39, is a critical ectoenzyme involved in the regulation of extracellular nucleotide levels. It belongs to the family of ectonucleoside triphosphate diphosphohydrolases (E-NTPDases) that hydrolyze extracellular nucleotides, such as ATP and ADP, into their respective monophosphate forms (AMP). This enzymatic activity is crucial for modulating purinergic signaling, which is involved in various physiological processes, including immune responses, thrombosis, vascular function, and tissue homeostasis. ENTPD1 is primarily expressed on immune cells like T regulatory cells (Tregs), dendritic cells, macrophages, and endothelial cells. Its ability to degrade ATP and ADP limits pro-inflammatory and pro-thrombotic signaling, promoting an anti-inflammatory and antithrombotic environment. This makes ENTPD1 a significant player in maintaining immune tolerance, regulating inflammation, and controlling thrombosis.
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