COP9 Signalosome Subunit 5 (COPS5) Antibody

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52€ (10 µg)

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935106861
info@markelab.com
name
COP9 Signalosome Subunit 5 (COPS5) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx013737
tested applications
ELISA, WB

Description

Rabbit polyclonal antibody against COPS5 protein. Immunogen region is Internal.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
COP9 Signalosome Subunit 5 (COPS5)
Host
Rabbit
Reactivity
Human, Mouse
Recommended Dilution
WB: 1/500 - 1/3000, ELISA: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen.
Size 1
10 µg
Size 2
100 µg
Size 3
200 µg
Size 4
300 µg
Size 5
1 mg
Form
Liquid
Tested Applications
ELISA, WB
Buffer
PBS (without Mg<sup>2+</sup> and Ca<sup>2+</sup>), pH 7.4, 150 mM NaCl, 0.02% sodium azide, 50% glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q92905
Background
Antibody anti-COPS5
Status
RUO
Note
Concentration: 1 mg/ml -

Descripción

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COP9 Signalosome Subunit 5 (COPS5) Antibody

COPS5 Antibody is a Rabbit Polyclonal antibody against COPS5. The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors.

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