COP9 Constitutive Photomorphogenic Homolog Subunit 6 (COPS6) Antibody
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Description
COPS6 Antibody is a Rabbit Polyclonal antibody against COPS6. The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein belongs to translation initiation factor 3 (eIF3) superfamily. It is involved in the regulation of cell cycle and likely to be a cellular cofactor for HIV-1 accessory gene product Vpr.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: COP9 Constitutive Photomorphogenic Homolog Subunit 6 (COPS6) Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 58-327 of human COPS6. |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Assay Type | Concentration: > 0.2 mg/ml |
| Recommended Dilution | ELISA: 1 µg/ml, WB: 1/100 - 1/500, IF/ICC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Calculated MW: 36 kDa Observed MW: 35 kDa |
| Purification | Purified by affinity chromatography. |
| Size 1 | 20 µl |
| Size 2 | 100 µl |
| Size 3 | 2 × 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IF/ICC |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q7L5N1 |
| Gene ID | 10980 |
| NCBI Accession | NP_006824.2 |
| Background | Antibody anti-COPS6 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
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COP9 Constitutive Photomorphogenic Homolog Subunit 6 (COPS6) Antibody
COPS6 Antibody is a Rabbit Polyclonal antibody against COPS6. The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein belongs to translation initiation factor 3 (eIF3) superfamily. It is involved in the regulation of cell cycle and likely to be a cellular cofactor for HIV-1 accessory gene product Vpr.
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COP9 Constitutive Photomorphogenic Homolog Subunit 6 (COPS6) Antibody
COPS6 Antibody is a Rabbit Polyclonal against COPS6.
Ver ProductoCOP9 Constitutive Photomorphogenic Homolog Subunit 6 (COPS6) Antibody
COP9 Constitutive Photomorphogenic Homolog Subunit 6 (COPS6) Antibody is a Rabbit Polyclonal antibody against COP9 Constitutive Photomorphogenic Homolog Subunit 6 (COPS6).
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