Contactin 6 (CNTN6) Antibody
273€ (200 µl)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Contactin 6 (CNTN6) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx430922
tested applications
P-ELISA
Description
Contactin 6 Antibody is a Goat Polyclonal antibody against Contactin 6.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Contactin 6 (CNTN6) |
| Host | Goat |
| Recommended Dilution | P-ELISA: 1/128000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Size 1 | 200 µl |
| Form | Liquid |
| Tested Applications | P-ELISA |
| Buffer | Tris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Gene ID | 27255, 53870 |
| NCBI Accession | NP_059079.2 |
| Alias | NB3,Neural recognition molecule NB-3,hNB-3,Contactin-6 |
| Background | Antibody anti-CNTN6 |
| Status | RUO |
| Note | Concentration: 0.5 mg/ml - |
Descripción
Contactin 6 (CNTN6), also referred to as NB-3, is a neuronal cell adhesion molecule that is highly expressed in the brain and spinal cord during development. It regulates axon guidance, neuronal migration, and synapse formation, particularly in corticospinal tract development and cerebellar circuit organization. CNTN6 interacts with other contactins and neural receptors to facilitate synaptic connectivity and plasticity, contributing to the establishment of neural networks involved in motor control and coordination. Genetic studies have implicated CNTN6 in neurodevelopmental disorders such as autism spectrum disorders (ASD) and intellectual disability, where its dysregulation disrupts neuronal connectivity and cognitive functions. In addition to its roles in development, CNTN6 expression persists in the adult nervous system, suggesting ongoing functions in synaptic maintenance and plasticity. Structurally, CNTN6 features extracellular immunoglobulin-like and fibronectin type III domains, which mediate its adhesive and signaling interactions. Emerging research also highlights its potential involvement in neuropathological conditions, including neurodegenerative diseases and peripheral neuropathies.
Related Products
Contactin 6 (CNTN6) Antibody
Rabbit polyclonal antibody against CNTN6 protein. Immunogen region is Internal.
Ver Producto
Contactin 6 (CNTN6) Antibody
Contactin 6 Antibody is a Rabbit Polyclonal against Contactin 6.
Ver Producto
Mouse Contactin 6 (CNTN6) Protein
Contactin 6 Protein is a recombinant Mouse protein expressed in E. coli.
Ver Producto