Contactin 4 (CNTN4) Antibody
169€ (20 µl)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Contactin 4 (CNTN4) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx321202
Tested Applications
ELISA, IHC
Description
CNTN4 Antibody is a Rabbit Polyclonal against CNTN4.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Contactin 4 (CNTN4) Immunogen: Recombinant human Contactin-4 protein (777-1026AA). |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 20 µl |
| Size 2 | 50 µl |
| Size 3 | 100 µl |
| Size 4 | 200 µl |
| Size 5 | 1 ml |
| Form | Liquid |
| Tested Applications | ELISA, IHC |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q8IWV2 |
| Gene ID | 152330 |
| NCBI Accession | NP_001193884.1, NM_001206955.1 |
| OMIM | 607280 |
| Alias | AXCAM,BIG-2, Brain-derived immunoglobulin superfamily protein 2,Contactin-4 |
| Background | Antibody anti-CNTN4 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Contactin 4 (CNTN4), a GPI-anchored member of the immunoglobulin superfamily, is predominantly expressed in the central nervous system, where it regulates neuronal development and synaptic connectivity. CNTN4 is involved in axon guidance, neuronal migration, and synapse formation by mediating homophilic and heterophilic cell-cell interactions. It interacts with other neural cell adhesion molecules and receptors to establish neural circuits during development, particularly in the auditory and visual systems. CNTN4 has been implicated in neurodevelopmental disorders, including autism spectrum disorders (ASD) and attention-deficit hyperactivity disorder (ADHD), where its dysregulation affects neural connectivity and cognitive function. Structural studies reveal that CNTN4 contains extracellular immunoglobulin-like and fibronectin type III domains, which facilitate dynamic interactions essential for its role in neural development. Beyond its role in the nervous system, CNTN4 is also expressed in non-neural tissues, where it may contribute to cell adhesion and signaling in developmental and pathological contexts.
Productos relacionados
Contactin 4 (CNTN4) Antibody
Rabbit polyclonal antibody against CNTN4 protein. Immunogen region is Internal.…
Ver producto
Human Contactin 4 (CNTN4) Protein
Human Contactin 4 (CNTN4) is a recombinant Human protein expressed in E. coli.…
Ver producto