Complement Receptor Type 1 / CD35 (CR1) Antibody

Este producto es parte de CR1 - complement C3b/C4b receptor 1
Product Graph
299€ (0.1 mg)

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935106861
info@markelab.com
name
Complement Receptor Type 1 / CD35 (CR1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx139371
tested applications
IHC, IF/ICC, FCM, IP

Description

CD35 Antibody is a Mouse Monoclonal against CD35.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Complement Receptor Type 1 / CD35 (CR1)
Host
Mouse
Reactivity
Human, Monkey
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Clonality
Monoclonal
Conjugation
Unconjugated
Isotype
IgG1
Clone ID
L881
Purity
> 95% (SDS-PAGE)
Purification
Purified by Protein A affinity chromatography.
Size 1
0.1 mg
Tested Applications
IHC, IF/ICC, FCM, IP
Buffer
PBS solution with 15 mM sodium azide.
Availability
Shipped within 5-12 working days.
Storage
Store at 2-8°C. Do not freeze.
Dry Ice
No
UniProt ID
P17927
Gene ID
1378
Alias
KN,C3BR,C4BR,CD35,Knops blood group,Complement receptor type 1,C3b/C4b receptor
Background
Antibody anti-CR1
Status
RUO
Note
Concentration: 1 mg/ml - 

Descripción

CR1 (Complement Receptor 1), also known as CD35, is a membrane-bound glycoprotein that plays a key role in the immune system, primarily in mediating the clearance of immune complexes, apoptotic cells, and pathogens through its interaction with components of the complement system. CR1 acts as a receptor for complement proteins C3b and C4b, which are opsonins involved in the activation of the classical and alternative complement pathways. These pathways are critical for enhancing phagocytosis and immune complex clearance, ultimately contributing to host defense against infections. CR1 is expressed on a variety of immune cells, including erythrocytes (red blood cells), leukocytes, monocytes, macrophages, neutrophils, B cells, follicular dendritic cells, and kidney podocytes. The expression pattern of CR1 allows it to fulfill diverse immunological functions, such as regulating complement activation, promoting phagocytosis, and serving as a cofactor for complement cleavage and degradation.

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