Complement Component 5a Receptor 1 (C5AR1) Antibody (APC)
429€ (100 tests)
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935106861
info@markelab.com
name
Complement Component 5a Receptor 1 (C5AR1) Antibody (APC)
category
Primary Antibodies
provider
Abbexa
reference
abx347248
tested applications
FCM
Description
Complement Component 5a Receptor 1 (C5AR1) Antibody (APC) is a APC-conjugated Mouse monoclonal antibody for the detection of Complement Component 5a Receptor 1 (C5AR1).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Complement Component 5a Receptor 1 (C5AR1) |
| Host | Mouse |
| Reactivity | Human, Cow, Rabbit, Ferret |
| Recommended Dilution | FCM: 10 µl/100 µl whole blood or 106 cells. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | APC |
| Isotype | IgG2a Kappa |
| Clone ID | M189 |
| Purification | Purified by size-exclusion chromatography. |
| Size 1 | 100 tests |
| Form | Liquid |
| Tested Applications | FCM |
| Buffer | PBS, pH 7.4, 15 mM sodium azide. |
| Availability | Shipped within 7-15 working days. |
| Storage | Store at 2-8°C in the dark. Do not freeze. |
| Dry Ice | No |
| UniProt ID | P21730 |
| Gene ID | 728 |
| Alias | C5AR1,CD88,C5A,C5AR,C5R1,C5a anaphylatoxin chemotactic receptor,C5a-R,complement C5a receptor,complement component 5a receptor 1 |
| Background | Antibody anti-C5AR1 |
| Status | RUO |
Descripción
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C5AR1 antibody
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a(PubMed:1847994, PubMed:8182049, PubMed:7622471, PubMed:9553099, PubMed:10636859, PubMed:15153520). The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events(PubMed:8182049, PubMed:7622471, PubMed:9553099). Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production(PubMed:10636859, PubMed:15153520).
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