Complement C5a (C5a) Antibody Pair

Este producto es parte de Complement C5
Complement C5a (C5a) Antibody Pair

Pida mas información

935106861

info@markelab.com

Precio

1235€ (5 × 96 tests)

Antibody Pair for C5

proveedor

Abbexa

reference

abx370235

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Complement Component 5a (C5a) Antibody Pair for use in Sandwich ELISA assay development.

Background

C5 is a central component of the complement system and plays a key role in the final steps of the complement cascade C5 is cleaved into C5a and C5b, with C5a acting as a potent inflammatory mediator that recruits immune cells to sites of infection or injury, and C5b contributing to the formation of the membrane attack complex (MAC), which leads to the lysis of pathogens C5 is involved in both innate and adaptive immune responses, helping to clear pathogens, regulate inflammation, and promote tissue repair Dysfunction in C5 or its components is associated with several diseases, including complement deficiencies, where insufficient activation leads to increased susceptibility to infections, and autoimmune disorders like atypical hemolytic uremic syndrome (aHUS) Studies also suggest that C5 plays a role in cancer progression, where its activity can influence immune evasion and tumor microenvironment regulation

Características del producto

category

Antibody Pairs

reactivity

Human

immunogen target

Complement C5a (C5a)

form

Standard: Lyophilized--Liquid (Capture Antibody and Detection Antibody) Reconstitute the standard with Standard Diluent. The volume, and therefore standard concentration, should be determined by the end user.

tested applications

ELISA

size 1

5 × 96 tests

size 2

10 × 96 tests

recommended dilution

Dilute the Capture Antibody 125-fold with Coating Buffer. Dilute the Biotin-Conjugated Detection Antibody 200-fold with Detection Antibody Diluent. Optimal dilutions/concentrations should be determined by the end user.

buffer

The Capture and Detection Antibody both contain 0.1% sodium azide.

storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

or code

C5

dry ice

No

availability

Please enquire.

alias

C5D,C5a,C5b,ECLZB,CPAMD4,C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4

uniprot id

https://www.uniprot.org/uniprotkb/P01031

note

This antibody pair contains ( 5 x 96 det): Detection: 50 µg Capture: 200 µg Standard: 2 µg This product is for research use only.

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