Complement C4a anaphylatoxin (C4a) Antibody
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935106861
info@markelab.com
Precio
273€ (100 µl)
Antibody anti-C4A
proveedor
Abbexareference
abx128779Tested Applications
WB, IHCreactivity
Humanstatus
RUOclonality
PolyclonalDescripción
Complement Fragment C4a (C4a) Antibody is a Rabbit Polyclonal against Complement Fragment C4a (C4a).
Background
C4B is a component of the classical and lectin pathways of the complement system, which plays an essential role in immune defense by promoting pathogen clearance, inflammation, and immune complex removal C4B is involved in the formation of the C3 convertase complex, which activates the complement cascade and results in the destruction of pathogens via opsonization and lysis It also participates in the regulation of immune responses and plays a role in clearing immune complexes that could otherwise contribute to tissue damage C4B is implicated in the Chido/Rodgers blood group system, which is used in transfusion medicine C4B deficiency or dysfunction is associated with autoimmune diseases, including systemic lupus erythematosus, where excessive complement activation exacerbates tissue damage The balance of C4B in the complement system is crucial for maintaining immune homeostasis and preventing chronic inflammation
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human
immunogen target
Complement Fragment C4a (C4a)
host
Rabbit
conjugation
Unconjugated
form
Liquid
tested applications
WB, IHC
purification
Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography.
recommended dilution
WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user.
buffer
0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol.
size 1
100 µl
size 2
200 µl
size 3
1 ml
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
C4A
dry ice
No
availability
Shipped within 5-7 working days.
alias
CH,C4F,CO4,C4B1,C4B2,C4B3,C4B5,C4BD,C4B12,C4B_2,CPAMD3,Basic complement C4,C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3
uniprot id
note
Concentration: 0.33 mg/ml -
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