Complement C2 (C2) Antibody
292.5€ (80 µl)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Complement C2 (C2) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx025830
Tested Applications
ELISA, WB
Description
Complement C2 (C2) is a serum glycoprotein that functions as part of the classical pathway of the complement system. Activated C1 cleaves C2 into C2a and C2b. The serine proteinase C2a then combines with complement factor 4b to create the C3 or C5 convertase. Deficiency of C2 has been reported to associated with certain autoimmune diseases and SNPs in this gene have been associated with altered susceptibility to age-related macular degeneration. This gene localizes within the class III region of the MHC on the short arm of chromosome 6. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described in publications but their full-length sequence has not been determined.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Complement C2 (C2) Immunogen: KLH-conjugated synthetic peptide between 147-176 amino acids from the N-terminal region of human C2. |
| Host | Rabbit |
| Reactivity | Human, Hamster |
| Recommended Dilution | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Calculated MW: 83.3 kDa |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P06681 |
| Gene ID | 717 |
| OMIM | 217000 |
| Background | Antibody anti-C2 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Productos relacionados
Complement C2 (C2) Antibody
Complement C2 (C2) is a serum glycoprotein that functions as part of the classical pathway of the complement system. Act…
Ver producto
Human Complement C2 (C2) Protein
Human Complement C2 (C2) is a recombinant Human protein expressed in E. coli.…
Ver producto