Collagen Type II Alpha 1 (COL2A1) Antibody
195€ (20 µl)
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Name
Collagen Type II Alpha 1 (COL2A1) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx001311
Tested Applications
ELISA, WB, IHC, IF/ICC
Description
COL2A1 Antibody is a Rabbit Polyclonal antibody against COL2A1. This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Collagen Type II Alpha 1 (COL2A1) Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1220-1282 of human COL2A1. |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Assay Type | Concentration: > 0.2 mg/ml |
| Recommended Dilution | ELISA: 1 µg/ml, WB: 1/500 - 1/1000, IHC-P: 1/1000 - 1/5000, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Calculated MW: 142 kDa Observed MW: 141 kDa |
| Purification | Purified by affinity chromatography. |
| Size 1 | 20 µl |
| Size 2 | 100 µl |
| Size 3 | 2 × 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Buffer | PBS, pH 7.3, containing 0.09% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P02458 |
| Gene ID | 1280 |
| NCBI Accession | NP_001835.3 |
| Background | Antibody anti-COL2A1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
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