CMRF35-Like Molecule 8 (CD300A) Antibody

169€ (20 µl)
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935106861
info@markelab.com
name
CMRF35-Like Molecule 8 (CD300A) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx322634
tested applications
ELISA, WB, IHC
Description
CD300A Antibody is a Rabbit Polyclonal against CD300A.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Primary Antibodies |
Immunogen Target | CMRF35-Like Molecule 8 (CD300A) |
Host | Rabbit |
Reactivity | Human, Mouse |
Recommended Dilution | WB: 1/1000 - 1/5000, IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Purification | Antigen Affinity Chromatography. |
Size 1 | 20 µl |
Size 2 | 50 µl |
Size 3 | 100 µl |
Size 4 | 200 µl |
Size 5 | 1 ml |
Form | Liquid |
Tested Applications | ELISA, WB, IHC |
Buffer | PBS, pH 7.3, containing 0.02% sodium azide and 50% glycerol. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | Q9UGN4 |
Gene ID | 11314 |
NCBI Accession | NP_001243770.1, NM_001256841.1, NP_001317386.1, NM_001330457.1, NP_009192.2, NM_007261.3 |
OMIM | 606790 |
Alias | CMRF35H,IGSF12,CMRF-35-H9,CMRF35-H9,IRC1/IRC2,Immunoglobulin superfamily member 12 |
Background | Antibody anti-CD300A |
Status | RUO |
Descripción
CD300A, also known as immune receptor expressed by myeloid cells (IREM-1) or leukocyte mono-immunoglobulin-like receptor 8 (LMIR8), is a member of the CD300 family of immunoreceptors. This molecule plays a significant role in the regulation of immune responses. It is encoded by the CD300A gene located on the human chromosome 17. CD300A is primarily expressed on the surface of myeloid cells, including monocytes, macrophages, dendritic cells, and some subsets of lymphocytes. The CD300 family consists of several members, each contributing to the regulation of immune cell functions. CD300A, in particular, is recognized for its inhibitory functions, helping to maintain immune homeostasis and preventing overactivation that could lead to autoimmunity.
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