CMRF35-Like Molecule 8 (CD300A) Antibody

357.5€ (100 µg)
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935106861
info@markelab.com
name
CMRF35-Like Molecule 8 (CD300A) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx146214
tested applications
ELISA, WB
Description
CD300A Antibody is a Rabbit Polyclonal against CD300A.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: CMRF35-Like Molecule 8 (CD300A) Immunogen: Recombinant fragment corresponding to 27-180 AA of human CD300A. |
| Host | Rabbit |
| Reactivity | Human |
| Assay Type | Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. |
| Recommended Dilution | ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Observed MW: 60 kDa |
| Purification | Purified by Protein A/G column chromatography. |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Lyophilized |
| Tested Applications | ELISA, WB |
| Buffer | Prior to lyophilization: 0.02% NaN3. |
| Availability | Shipped within 7-15 working days. |
| Storage | Store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| NCBI Accession | BC032352 |
| Alias | CMRF35H,IGSF12,CMRF-35-H9,CMRF35-H9,IRC1/IRC2,Immunoglobulin superfamily member 12 |
| Background | Antibody anti-CD300A |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
CD300A, also known as immune receptor expressed by myeloid cells (IREM-1) or leukocyte mono-immunoglobulin-like receptor 8 (LMIR8), is a member of the CD300 family of immunoreceptors. This molecule plays a significant role in the regulation of immune responses. It is encoded by the CD300A gene located on the human chromosome 17. CD300A is primarily expressed on the surface of myeloid cells, including monocytes, macrophages, dendritic cells, and some subsets of lymphocytes. The CD300 family consists of several members, each contributing to the regulation of immune cell functions. CD300A, in particular, is recognized for its inhibitory functions, helping to maintain immune homeostasis and preventing overactivation that could lead to autoimmunity.
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