Cluster of Differentiation 83 (CD83) Antibody
312€ (60 µl)
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935106861
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name
Cluster of Differentiation 83 (CD83) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx001657
tested applications
WB
Description
CD83 Antibody is a Rabbit Polyclonal antibody against CD83. The protein encoded by this gene is a single-pass type I membrane protein and member of the immunoglobulin superfamily of receptors. The encoded protein may be involved in the regulation of antigen presentation. A soluble form of this protein can bind to dendritic cells and inhibit their maturation. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011].
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Cluster of Differentiation 83 (CD83) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 60 µl |
| Size 2 | 120 µl |
| Size 3 | 200 µl |
| Form | Liquid |
| Tested Applications | WB |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q01151 |
| Gene ID | 9308 |
| NCBI Accession | NP_004224.1 |
| Alias | BL11,HB15,B-cell activation protein,Cell surface protein HB15,Hcd83,CD83 antigen |
| Background | Antibody anti-CD83 |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
CD83 is a transmembrane glycoprotein that belongs to the immunoglobulin (Ig) superfamily. It is encoded by the CD83 gene located on chromosome 6p23. CD83 was initially identified on activated lymphocytes and is now recognized as a critical molecule in the regulation of immune responses. The protein is primarily expressed on the surface of mature dendritic cells (DCs), activated T cells, B cells, and other immune cells. CD83 plays a vital role in the immune system by influencing the maturation and function of immune cells, making it a significant molecule in immunology.
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