Cluster of Differentiation 82 (CD82) Antibody
364€ (100 µg)
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935106861
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name
Cluster of Differentiation 82 (CD82) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx231502
tested applications
ELISA, WB, IHC
Description
CD82 Antibody is a Rabbit Polyclonal against CD82.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Cluster of Differentiation 82 (CD82) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1/500 - 1/2000, IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P27701 |
| Gene ID | 3732 |
| OMIM | 600623 |
| Alias | R2,4F9,C33,IA4,ST6,GR15,KAI1,SAR2,TSPAN27,CD82 antigen,Inducible membrane protein R2,Metastasis suppressor Kangai-1,Suppressor of tumorigenicity 6 protein,Tetraspanin-27 |
| Background | Antibody anti-CD82 |
| Status | RUO |
| Note | Concentration: 2 mg/ml - Validity: 12 months. |
Descripción
CD82, also known as KAI1 (Kangai 1), is a member of the tetraspanin family, a group of integral membrane proteins involved in the regulation of cell development, motility, adhesion, and immune responses. CD82 is of particular interest in cancer biology due to its role as a metastasis suppressor gene. It was initially identified as a tumor suppressor in prostate cancer, and subsequent studies have demonstrated that it plays a significant role in suppressing metastasis across a range of cancers. The CD82 gene is located on chromosome 11p11.2 and is ubiquitously expressed in various cell types, including epithelial cells, immune cells, and neurons. The primary function of CD82 is to regulate cell-cell interactions and modulate signal transduction pathways. Importantly, CD82 is involved in the regulation of immune cell activation, adhesion, and migration, making it a vital component in both immune responses and cancer progression.
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