CD82 antibody

Este producto es parte de CD82 - CD82 molecule
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935106861
info@markelab.com
name
CD82 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab09921
tested applications
ELISA, WB, IHC

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
CD82 molecule (CD82)
Host
Mouse
Reactivity
Human, mouse
Recommended Dilution
WB: 1:1000-1:4000; IHC: 1:1000-1:3000
Clonality
monoclonal
Conjugation
Unconjugated
Isotype
IgG2a
Clone ID
4C7
Observed MW
48 kDa
Purity
≥95% as determined by SDS-PAGE
Purification
protein A+G purified
Size 1
100µg
Form
liquid
Tested Applications
ELISA, WB, IHC
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt ID
P27701
Gene ID
3732
Alias
R2,4F9,C33,IA4,ST6,GR15,KAI1,SAR2,TSPAN27,CD82 antigen,Inducible membrane protein R2,Metastasis suppressor Kangai-1,Suppressor of tumorigenicity 6 protein,Tetraspanin-27
Background
Antibody anti-CD82
Status
RUO
Note
Mol. Weight 48 kDa

CD82, also known as KAI1 (Kangai 1), is a member of the tetraspanin family, a group of integral membrane proteins involved in the regulation of cell development, motility, adhesion, and immune responses. CD82 is of particular interest in cancer biology due to its role as a metastasis suppressor gene. It was initially identified as a tumor suppressor in prostate cancer, and subsequent studies have demonstrated that it plays a significant role in suppressing metastasis across a range of cancers. The CD82 gene is located on chromosome 11p11.2 and is ubiquitously expressed in various cell types, including epithelial cells, immune cells, and neurons. The primary function of CD82 is to regulate cell-cell interactions and modulate signal transduction pathways. Importantly, CD82 is involved in the regulation of immune cell activation, adhesion, and migration, making it a vital component in both immune responses and cancer progression.

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