CD82 antibody

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935106861
info@markelab.com
name
CD82 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab09921
tested applications
ELISA, WB, IHC
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | CD82 molecule (CD82) |
Host | Mouse |
Reactivity | Human, mouse |
Recommended Dilution | WB: 1:1000-1:4000; IHC: 1:1000-1:3000 |
Clonality | monoclonal |
Conjugation | Unconjugated |
Isotype | IgG2a |
Clone ID | 4C7 |
Observed MW | 48 kDa |
Purity | ≥95% as determined by SDS-PAGE |
Purification | protein A+G purified |
Size 1 | 100µg |
Form | liquid |
Tested Applications | ELISA, WB, IHC |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
UniProt ID | P27701 |
Gene ID | 3732 |
Alias | R2,4F9,C33,IA4,ST6,GR15,KAI1,SAR2,TSPAN27,CD82 antigen,Inducible membrane protein R2,Metastasis suppressor Kangai-1,Suppressor of tumorigenicity 6 protein,Tetraspanin-27 |
Background | Antibody anti-CD82 |
Status | RUO |
Note | Mol. Weight 48 kDa |
CD82, also known as KAI1 (Kangai 1), is a member of the tetraspanin family, a group of integral membrane proteins involved in the regulation of cell development, motility, adhesion, and immune responses. CD82 is of particular interest in cancer biology due to its role as a metastasis suppressor gene. It was initially identified as a tumor suppressor in prostate cancer, and subsequent studies have demonstrated that it plays a significant role in suppressing metastasis across a range of cancers. The CD82 gene is located on chromosome 11p11.2 and is ubiquitously expressed in various cell types, including epithelial cells, immune cells, and neurons. The primary function of CD82 is to regulate cell-cell interactions and modulate signal transduction pathways. Importantly, CD82 is involved in the regulation of immune cell activation, adhesion, and migration, making it a vital component in both immune responses and cancer progression.
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