Cluster of Differentiation 81 (CD81) Antibody (PE)

Este producto es parte de CD81 - CD81 molecule
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546€ (100 tests)

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935106861
info@markelab.com
name
Cluster of Differentiation 81 (CD81) Antibody (PE)
category
Primary Antibodies
provider
Abbexa
reference
abx270809
tested applications
FCM

Description

Cluster of Differentiation 81 (CD81) Antibody (PE) is a Rabbit Polyclonal Antibody conjugated to PE against Cluster of Differentiation 81 (CD81) for use in flow cytometry.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Cluster of Differentiation 81 (CD81)
Host
Rabbit
Reactivity
Human
Recommended Dilution
FCM: 1-5 µl/106 cells. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
PE
Isotype
IgG
Purification
Purified by antigen-specific affinity chromatography.
Size 1
100 tests
Size 2
200 tests
Size 3
500 tests
Form
Liquid
Tested Applications
FCM
Buffer
0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol.
Availability
Shipped within 5-15 working days.
Storage
Aliquot and store at 2°C to 8°C upon receipt. Avoid exposure to light.
Dry Ice
No
Alias
CVID6,S5.7,CD81 antigen,26 kDa cell surface protein TAPA-1,Target of the antiproliferative antibody 1,Tetraspanin-28,Tspan-28,
Background
Antibody anti-CD81
Status
RUO

Descripción

CD81, also known as TAPA-1 (Target of the Anti-Proliferative Antibody 1), is a member of the tetraspanin family, a group of proteins that are widely expressed across various tissues and cell types. Tetraspanins are integral membrane proteins involved in a variety of biological processes, including cell adhesion, migration, proliferation, and signal transduction. CD81 has a well-established role in immune cell function, particularly in the regulation of B and T cell activity, as well as in viral infections. Most notably, CD81 is a critical component in the entry process of hepatitis C virus (HCV) into host cells. The CD81 gene is located on chromosome 11p15.5 and encodes a protein that is involved in the formation of tetraspanin-enriched microdomains. These microdomains facilitate the assembly of various signaling complexes at the cell membrane, influencing the function of associated proteins. CD81 is widely expressed on multiple cell types, including lymphocytes, hepatocytes, epithelial cells, and fibroblasts

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