Cluster of Differentiation 81 (CD81) Antibody (APC / Cyanine 7)
468€ (100 tests)
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935106861
info@markelab.com
name
Cluster of Differentiation 81 (CD81) Antibody (APC / Cyanine 7)
category
Primary Antibodies
provider
Abbexa
reference
abx140932
tested applications
FCM
Description
Cluster of Differentiation 81 (CD81) Antibody (APC / Cyanine 7) is a Mouse against Cluster of Differentiation 81 (CD81).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Cluster of Differentiation 81 (CD81) |
| Host | Mouse |
| Reactivity | Human, Rabbit, Cat |
| Conjugation | APC / Cyanine 7 |
| Isotype | IgG1 |
| Clone ID | U151 |
| Size 1 | 100 tests |
| Tested Applications | FCM |
| Buffer | Stabilizing PBS solution containing 15 mM sodium azide. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store in the dark at 2-8°C. Avoid exposure to light. Do not freeze. |
| Dry Ice | No |
| UniProt ID | P60033 |
| Gene ID | 975 |
| Alias | CVID6,S5.7,CD81 antigen,26 kDa cell surface protein TAPA-1,Target of the antiproliferative antibody 1,Tetraspanin-28,Tspan-28, |
| Background | Antibody anti-CD81 |
| Status | RUO |
Descripción
CD81, also known as TAPA-1 (Target of the Anti-Proliferative Antibody 1), is a member of the tetraspanin family, a group of proteins that are widely expressed across various tissues and cell types. Tetraspanins are integral membrane proteins involved in a variety of biological processes, including cell adhesion, migration, proliferation, and signal transduction. CD81 has a well-established role in immune cell function, particularly in the regulation of B and T cell activity, as well as in viral infections. Most notably, CD81 is a critical component in the entry process of hepatitis C virus (HCV) into host cells. The CD81 gene is located on chromosome 11p15.5 and encodes a protein that is involved in the formation of tetraspanin-enriched microdomains. These microdomains facilitate the assembly of various signaling complexes at the cell membrane, influencing the function of associated proteins. CD81 is widely expressed on multiple cell types, including lymphocytes, hepatocytes, epithelial cells, and fibroblasts
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