Cluster of Differentiation 40 Ligand / TNFSF5 (CD40LG) Antibody (HRP)
169€ (20 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Cluster of Differentiation 40 Ligand / TNFSF5 (CD40LG) Antibody (HRP)
Category
Primary Antibodies
Provider
Abbexa
Reference
abx306370
Tested Applications
ELISA
Description
CD40LG Antibody (HRP) is a Rabbit Polyclonal against CD40LG conjugated to HRP.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Cluster of Differentiation 40 Ligand / TNFSF5 (CD40LG) Immunogen: Recombinant human CD40 ligand protein (47-258AA). |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | HRP |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P29965 |
| Gene ID | 959 |
| OMIM | 300386 |
| Alias | T-cell antigen Gp39,IGM,IMD3,TRAP,gp39,CD154,CD40L,HIGM1,T-BAM,TNFSF5,hCD40L,TNF-related activation protein,Tumor necrosis factor ligand superfamily member 5 |
| Background | Antibody anti-CD40LG |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
CD40 ligand (CD40LG), also known as CD154 or TNFSF5, is a transmembrane protein expressed primarily on the surface of activated T cells and, to a lesser extent, on platelets and other cell types. It is a key member of the tumor necrosis factor (TNF) superfamily and functions as a ligand for CD40, a receptor found on the surface of various immune cells, including B cells, dendritic cells, macrophages, and endothelial cells. CD40LG-CD40 interactions are essential for effective immune responses, promoting T-cell-B-cell cooperation, antigen presentation, and the production of antibodies. Mutations in CD40LG are linked to X-linked hyper-IgM syndrome (XHIM), a primary immunodeficiency disorder, highlighting the protein's importance in immune system regulation. The CD40LG-CD40 axis also plays a role in the development of autoimmune diseases, cardiovascular disorders, and cancer, where the interaction is implicated in chronic inflammation and pathological immune activation.
Productos relacionados
Cluster of Differentiation 40 Ligand / TNFSF5 (CD40LG) Antibody
CD40LG Antibody is a Rabbit Polyclonal antibody against CD40LG. The protein encoded by this gene is expressed on the sur…
Ver producto Cluster of Differentiation 40 Ligand / TNFSF5 (CD40LG) Antibody
CD40L Antibody is a Mouse monoclonal antibody for human cds against CD40L.…
Ver producto Cluster of Differentiation 40 Ligand / TNFSF5 (CD40LG) Antibody
CD40L Antibody is a Mouse monoclonal antibody for human cds against CD40L.…
Ver producto