Cluster of Differentiation 276 (CD276) Antibody

Este producto es parte de CD276 molecule
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312€ (60 µl)

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935106861
info@markelab.com
name
Cluster of Differentiation 276 (CD276) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx125633
tested applications
WB, IHC

Description

CD276 Antibody is a Rabbit Polyclonal against CD276.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
Cluster of Differentiation 276 (CD276)
Host
Rabbit
Reactivity
Human
Recommended Dilution
WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified by affinity chromatography.
Size 1
60 µl
Size 2
120 µl
Size 3
200 µl
Form
Liquid
Tested Applications
WB, IHC
Buffer
PBS, pH 7.3, containing 0.01% thiomersal, 50% glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q5ZPR3
Gene ID
80381
NCBI Accession
NP_001019907.1
Alias
B7H3,B7-H3,B7RP-2,4Ig-B7-H3,B7 homolog 3,Costimulatory molecule
Background
Antibody anti-CD276
Status
RUO
Note
Concentration: 1 mg/ml - 

Descripción

CD276, also known as B7-H3, is a protein encoded by the CD276 gene located on chromosome 15q24.1. It is a member of the B7 family of immune regulatory molecules, which are known to play crucial roles in the modulation of immune responses. B7-H3 was first identified in 2001 and has since been recognized for its involvement in immune regulation, particularly in the context of cancer, autoimmunity, and transplantation. The expression of B7-H3 is widespread, found on various cell types, including dendritic cells, monocytes, activated T cells, and several non-immune cells such as fibroblasts, endothelial cells, and certain epithelial cells. Its expression can be induced by inflammatory cytokines and other immune signals.

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