Cluster of Differentiation 24 (CD24) Antibody
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
CD24 Antibody is a Rabbit Polyclonal against CD24.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Cluster of Differentiation 24 (CD24) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P25063 |
| Alias | CD24A,Signal transducer CD24,Small cell lung carcinoma cluster 4 antigen |
| Background | Antibody anti-CD24 |
| Status | RUO |
| Note | Concentration: 2 mg/ml - Validity: 12 months. |
Descripción
CD24 is a small, heavily glycosylated cell surface protein that plays a crucial role in modulating immune responses, cell adhesion, and signal transduction. It is expressed in a wide range of tissues, including hematopoietic cells, neurons, epithelial cells, and cancer cells. CD24 has gained significant attention for its role in the immune system and its involvement in cancer biology. It has been implicated in both autoimmune diseases and tumor progression, making it an important molecule for understanding various pathophysiological processes. CD24 is involved in modulating immune responses, particularly in the context of inflammation, tumor immunology, and autoimmunity. It acts as a key regulator of innate immunity by interacting with various receptors, such as Siglec-10 on macrophages, to dampen inflammatory responses and promote immune tolerance. In the tumor microenvironment, CD24 can contribute to the immune evasion of cancer cells, allowing them to escape destruction by the immune system.
Related Products
Human CD24(Signal transducer CD24) ELISA Kit
Ver Producto
anti- CD24 antibody
Modulates B-cell activation responses. Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Promotes AG-dependent proliferation of B-cells, and prevents their terminal differentiation into antibody-forming cells.
Ver Producto
anti- CD24 antibody
Modulates B-cell activation responses. Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Promotes AG-dependent proliferation of B-cells, and prevents their terminal differentiation into antibody-forming cells.
Ver Producto