Cluster of Differentiation 24 (CD24) Antibody

Este producto es parte de CD24 - CD24 molecule
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780€ (500 µg)

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935106861
info@markelab.com
name
Cluster of Differentiation 24 (CD24) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx413015
tested applications
IHC, FCM

Description

Signal Transducer CD24 (CD24) Antibody is a Mouse Monoclonal antibody against Signal Transducer CD24 (CD24).

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryPrimary Antibodies
Immunogen TargetCluster of Differentiation 24 (CD24)
HostMouse
ReactivityHuman
Recommended DilutionValidated in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
ClonalityMonoclonal
ConjugationUnconjugated
IsotypeIgG1
PurificationPurified
Size 1500 µg
FormLiquid
Tested ApplicationsIHC, FCM
BufferPBS.
AvailabilityShipped within 3-7 working days.
StorageAliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry IceNo
UniProt IDP25063
AliasCD24A,Signal transducer CD24,Small cell lung carcinoma cluster 4 antigen
BackgroundAntibody anti-CD24
StatusRUO
NoteConcentration: 1.0 mg/ml -

Descripción

CD24 is a small, heavily glycosylated cell surface protein that plays a crucial role in modulating immune responses, cell adhesion, and signal transduction. It is expressed in a wide range of tissues, including hematopoietic cells, neurons, epithelial cells, and cancer cells. CD24 has gained significant attention for its role in the immune system and its involvement in cancer biology. It has been implicated in both autoimmune diseases and tumor progression, making it an important molecule for understanding various pathophysiological processes. CD24 is involved in modulating immune responses, particularly in the context of inflammation, tumor immunology, and autoimmunity. It acts as a key regulator of innate immunity by interacting with various receptors, such as Siglec-10 on macrophages, to dampen inflammatory responses and promote immune tolerance. In the tumor microenvironment, CD24 can contribute to the immune evasion of cancer cells, allowing them to escape destruction by the immune system.

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