Cluster Of Differentiation 14 (CD14) Antibody is a Rabbit Polyclonal antibody for the detection of CD14. Coreceptor for bacterial lipopolysaccharide (PubMed:1698311, PubMed:23264655). In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS) (PubMed:20133493, PubMed:23264655). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (PubMed:8612135). Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway (PubMed:16880211).
Primary Antibodies
Polyclonal
Human
Cluster Of Differentiation 14 (CD14)
Rabbit
Unconjugated
Liquid
ELISA, IHC
≥ 95% (SDS-PAGE)
Purified by immunogen affinity chromatography.
PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
100 µg
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
CD14
No
Shipped within 5-12 working days.
Cluster Of Differentiation 14,CD14,Myeloid Cell-Specific Leucine-Rich Glycoprotein,Monocyte differentiation antigen CD14
This product is for research use only.
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Ver másCoreceptor for bacterial lipopolysaccharide(PubMed:1698311, PubMed:23264655). In concert with LBP, binds to monomeric li...
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