CLIP-Associating Protein 2 (CLASP2) Antibody
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Description
CLASP2 Antibody is a Rabbit Polyclonal antibody against CLASP2.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | CLIP-Associating Protein 2 (CLASP2) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 60 µl |
| Size 2 | 120 µl |
| Size 3 | 200 µl |
| Form | Liquid |
| Tested Applications | WB |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O75122 |
| Gene ID | 23122 |
| NCBI Accession | NP_001193973.1 |
| Background | Antibody anti-CLASP2 |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
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CLASP2 antibody
Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules(PubMed:26003921). Involved in the nucleation of noncentrosomal microtubules originating from the trans-Golgi network(TGN). Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2(PubMed:16824950). This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3-kinase signaling. Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle(PubMed:16866869, PubMed:16914514). Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex.
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CLIP-Associating Protein 2 (CLASP2) Antibody
CLASP2 Antibody is a Rabbit Polyclonal antibody against CLASP2.
Ver Producto
CLIP-Associating Protein 2 (CLASP2) Antibody
Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules. Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2. This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3-kinase signaling. Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle.
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