Cleavage And Polyadenylation Specificity Factor Subunit 5 (NUDT21) Antibody
195€ (20 µl)
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935106861
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name
Cleavage And Polyadenylation Specificity Factor Subunit 5 (NUDT21) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx003353
tested applications
ELISA, WB, IHC
Description
NUDT21 Antibody is a Rabbit Polyclonal antibody against NUDT21. The protein encoded by this gene is one subunit of a cleavage factor required for 3' RNA cleavage and polyadenylation processing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3' end processing complex and facilitates the recruitment of other processing factors. This gene encodes the 25kD subunit of the protein complex, which is composed of four polypeptides.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Cleavage And Polyadenylation Specificity Factor Subunit 5 (NUDT21) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | ELISA: 1 µg/ml, WB: 1/500 - 1/1000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 20 µl |
| Size 2 | 100 µl |
| Size 3 | 2 × 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O43809 |
| Gene ID | 11051 |
| NCBI Accession | NP_008937.1 |
| Background | Antibody anti-NUDT21 |
| Status | RUO |
| Note | Concentration: > 0.2 mg/ml - |
Descripción
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Component of the cleavage factor Im(CFIm) complex that plays a key role in pre-mRNA 3'-processing. Involved in association with CPSF6 or CPSF7 in pre-MRNA 3'-end poly(A) site cleavage and poly(A) addition. NUDT21/CPSF5 binds to cleavage and polyadenylation RNA substrates. The homodimer mediates simultaneous sequence-specific recognition of two 5'-UGUA-3' elements within the pre-mRNA. Binds to, but does not hydrolyze mono-and di-adenosine nucleotides. May have a role in mRNA export.
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