Ciliary Neurotrophic Factor Receptor Subunit Alpha (CNTFR) Antibody

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195€ (20 µl)

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935106861
info@markelab.com
name
Ciliary Neurotrophic Factor Receptor Subunit Alpha (CNTFR) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx002062
tested applications
ELISA, WB

Description

CNTFR Antibody is a Rabbit Polyclonal antibody against CNTFR. This gene encodes a member of the type 1 cytokine receptor family. The encoded protein is the ligand-specific component of a tripartite receptor for ciliary neurotrophic factor, which plays a critical role in neuronal cell survival, differentiation and gene expression. Binding of ciliary neurotrophic factor to the encoded protein recruits the transmembrane components of the receptor, gp130 and leukemia inhibitory factor receptor, facilitating signal transduction. Single nucleotide polymorphisms in this gene may be associated with variations in muscle strength, as well as early onset of eating disorders. Alternatively spliced transcript variants have been observed for this gene.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
Ciliary Neurotrophic Factor Receptor Subunit Alpha (CNTFR)
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
ELISA: 1 µg/ml, WB: 1/400 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified by affinity chromatography.
Size 1
20 µl
Size 2
100 µl
Size 3
2 × 100 µl
Form
Liquid
Tested Applications
ELISA, WB
Buffer
PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P26992
Gene ID
1271
NCBI Accession
NP_671693.1
Background
Antibody anti-CNTFR
Status
RUO
Note
Concentration: > 0.2 mg/ml - 

Descripción

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Ciliary Neurotrophic Factor Receptor Subunit Alpha (CNTFR) Antibody

CNTFR Antibody is a Rabbit Polyclonal antibody against CNTFR. This gene encodes a member of the type 1 cytokine receptor family. The encoded protein is the ligand-specific component of a tripartite receptor for ciliary neurotrophic factor, which plays a critical role in neuronal cell survival, differentiation and gene expression. Binding of ciliary neurotrophic factor to the encoded protein recruits the transmembrane components of the receptor, gp130 and leukemia inhibitory factor receptor, facilitating signal transduction. Single nucleotide polymorphisms in this gene may be associated with variations in muscle strength, as well as early onset of eating disorders. Alternatively spliced transcript variants have been observed for this gene.

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