Chromosome Segregation 1 Like (CSE1L) Antibody
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Description
Cse1 Chromosome Segregation 1-Like (Yeast) Antibody is a Rabbit Polyclonal antibody against Cse1 Chromosome Segregation 1-Like (Yeast).
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Chromosome Segregation 1 Like (CSE1L) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, containing 0.02% Sodium Azide and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P55060 |
| Gene ID | 1434 |
| NCBI Accession | NP_001243064.1, NM_001256135.1, NP_001307.2, NM_001316.3 |
| OMIM | 601342 |
| Background | Antibody anti-CSE1L |
| Status | RUO |
Descripción
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CSE1L antibody
Export receptor for importin-alpha. Mediates importin-alpha re-export from the nucleus to the cytoplasm after import substrates(cargos) have been released into the nucleoplasm. In the nucleus binds cooperatively to importin-alpha and to the GTPase Ran in its active GTP-bound form. Docking of this trimeric complex to the nuclear pore complex(NPC) is mediated through binding to nucleoporins. Upon transit of a nuclear export complex into the cytoplasm, disassembling of the complex and hydrolysis of Ran-GTP to Ran-GDP(induced by RANBP1 and RANGAP1, respectively) cause release of the importin-alpha from the export receptor. CSE1L/XPO2 then return to the nuclear compartment and mediate another round of transport. The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP-and GDP-bound forms of Ran between the cytoplasm and nucleus.
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Chromosome Segregation 1 Like (CSE1L) Antibody
Cse1 Chromosome Segregation 1-Like (Yeast) Antibody is a Rabbit Polyclonal antibody against Cse1 Chromosome Segregation 1-Like (Yeast).
Ver ProductoChromosome Segregation 1 Like (CSE1L) Antibody
CSE1L Antibody is a Rabbit Polyclonal antibody against CSE1L.
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