CHRNA7-FAM7A Fusion Protein (CHRFAM7A) Antibody

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Description
Chrna7 (Cholinergic Receptor, Nicotinic, Alpha 7, Exons 5-10) And Fam7A (Family With Sequence Similarity 7A, Exons A-E) Fusion Antibody is a Rabbit Polyclonal antibody against Chrna7 (Cholinergic Receptor, Nicotinic, Alpha 7, Exons 5-10) And Fam7A (Family With Sequence Similarity 7A, Exons A-E) Fusion.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | CHRNA7-FAM7A Fusion Protein (CHRFAM7A) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, containing 0.02% Sodium Azide and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q494W8 |
| Gene ID | 89832 |
| OMIM | 609756 |
| Background | Antibody anti-CHRFAM7A |
| Status | RUO |
Descripción
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CHRFAM7A antibody
The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The family member CHRNA7, which is located on chromosome 15 in a region associated with several neuropsychiatric disorders, is partially duplicated and forms a hybrid with a novel gene from the family with sequence similarity 7 (FAM7A). Alternative splicing has been observed, and two variants exist, for this hybrid gene. The N-terminally truncated products predicted by the largest open reading frames for each variant would lack the majority of the neurotransmitter-gated ion-channel ligand binding domain but retain the transmembrane region that forms the ion channel. Although current evidence supports transcription of this hybrid gene, translation of the nicotinic acetylcholine receptor-like protein-encoding open reading frames has not been confirmed.
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Chrna7 (Cholinergic Receptor, Nicotinic, Alpha 7, Exons 5-10) And Fam7A (Family With Sequence Similarity 7A, Exons A-E) Fusion Antibody is a Rabbit Polyclonal antibody against Chrna7 (Cholinergic Receptor, Nicotinic, Alpha 7, Exons 5-10) And Fam7A (Family With Sequence Similarity 7A, Exons A-E) Fusion.
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