Cholesterol 24-Hydroxylase (CYP46A1) Antibody
260€ (50 µg)
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935106861
info@markelab.com
name
Cholesterol 24-Hydroxylase (CYP46A1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx457570
tested applications
ELISA, WB, IHC
Description
Cholesterol 24-Hydroxylase (CYP46A1) Antibody is a Rabbit polyclonal antibody for the detection of Human Cholesterol 24-Hydroxylase (CYP46A1).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Cholesterol 24-Hydroxylase (CYP46A1) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | 0.01 M PBS, pH 7.4, 50% glycerol, 0.05% Proclin-300. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9Y6A2 |
| Gene ID | 10858 |
| NCBI Accession | NP_006659.1 |
| OMIM | 604087 |
| Background | Antibody anti-CYP46A1 |
| Status | RUO |
Descripción
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CYP46A1 antibody
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed in the brain, where it converts cholesterol to 24S-hydroxycholesterol. While cholesterol cannot pass the blood-brain barrier, 24S-hydroxycholesterol can be secreted in the brain into the circulation to be returned to the liver for catabolism.
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