CYP46A1 antibody

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935106861
info@markelab.com
name
CYP46A1 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab02167
tested applications
ELISA, WB, IHC

Description

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed in the brain, where it converts cholesterol to 24S-hydroxycholesterol. While cholesterol cannot pass the blood-brain barrier, 24S-hydroxycholesterol can be secreted in the brain into the circulation to be returned to the liver for catabolism.

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
cytochrome P450, family 46, subfamily A, polypeptide 1 (CYP46A1)
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:100
Clonality
polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
57 kDa
Purity
≥95% as determined by SDS-PAGE
Purification
Immunogen affinity purified
Size 1
100µg
Form
liquid
Tested Applications
ELISA, WB, IHC
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
UniProt ID
Q9Y6A2
Gene ID
10858
Alias
Cholesterol 24-hydroxylase (CH24H),Cholesterol 24-monooxygenase,Cholesterol 24S-hydroxylase,Cytochrome P450 46A1,CYP46A1,CYP46
Background
Antibody anti-CYP46A1
Status
RUO
Note
Mol. Weight 57 kDa

Descripción

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