Chloride Voltage-Gated Channel 7 (CLCN7) Antibody

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52€ (10 µg)

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935106861
info@markelab.com
name
Chloride Voltage-Gated Channel 7 (CLCN7) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx014352
tested applications
ELISA, WB

Description

Rabbit polyclonal antibody against CLCN7 protein. Immunogen region is N-terminal.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
Chloride Voltage-Gated Channel 7 (CLCN7)
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
WB: 1/500 - 1/3000, ELISA: 1/40000. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen.
Size 1
10 µg
Size 2
100 µg
Size 3
200 µg
Size 4
300 µg
Size 5
1 mg
Form
Liquid
Tested Applications
ELISA, WB
Buffer
PBS (without Mg<sup>2+</sup> and Ca<sup>2+</sup>), pH 7.4, 150 mM NaCl, 0.02% sodium azide, 50% glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P51798
Background
Antibody anti-CLCN7
Status
RUO
Note
Concentration: 1 mg/ml -

Descripción

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The product of this gene belongs to the CLC chloride channel family of proteins. Chloride channels play important roles in the plasma membrane and in intracellular organelles. This gene encodes chloride channel 7. Defects in this gene are the cause of osteopetrosis autosomal recessive type 4 (OPTB4), also called infantile malignant osteopetrosis type 2 as well as the cause of autosomal dominant osteopetrosis type 2 (OPTA2), also called autosomal dominant Albers-Schonberg disease or marble disease autosoml dominant. Osteopetrosis is a rare genetic disease characterized by abnormally dense bone, due to defective resorption of immature bone. OPTA2 is the most common form of osteopetrosis, occurring in adolescence or adulthood.

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