Chicken Protein Argonaute 3 / EIF2C3 (AGO3) ELISA Kit
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935106861
info@markelab.com
Precio
773.5€ (96 tests)
Elisa kits for AGO3
proveedor
Abbexareference
abx501293Tested Applications
ELISAreactivity
Chickenstatus
RUOclonality
Descripción
Chicken Protein argonaute-3 ELISA Kit is an ELISA kit against Chicken Protein argonaute-3 (EIF2C3).
Background
AGO3 is a member of the Argonaute protein family, playing a role in RNA-induced silencing complex (RISC)-mediated gene regulation. Similar to other Argonaute proteins, AGO3 contains a PAZ domain, which binds the 3' end of small RNAs, and a PIWI domain, but it lacks significant catalytic slicer activity. AGO3 is primarily involved in microRNA (miRNA)-mediated translational repression, aiding in the recruitment of other silencing machinery to target mRNAs. Although less characterized than AGO1 and AGO2, AGO3 is expressed ubiquitously and contributes to post-transcriptional gene silencing in processes such as developmental regulation, stress responses, and immune function. Dysregulation of AGO3 is associated with diseases such as cancer, where altered miRNA activity impacts oncogenic or tumor suppressor pathways, though its precise roles remain under investigation.
Características del producto
category
ELISA Kits
immunogen target
Protein Argonaute 3 / EIF2C3 (AGO3)
reactivity
Chicken
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
EIF2C3
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
AGO3
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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