Chicken B-Cell-Activating Factor BAFF (BAFF) CLIA Kit

Este producto es parte de TNFSF13B - TNF superfamily member 13B
Chicken B-Cell-Activating Factor BAFF (BAFF) CLIA Kit

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935106861

info@markelab.com

Precio

812.5€ (96 tests)

CLIA Kits TNFSF13B

proveedor

Abbexa

reference

abx496467

Tested Applications

CLIA

reactivity

Chicken

status

RUO

clonality

Descripción

Chicken B-Cell-Activating Factor BAFF (BAFF) Chemiluminescent Immunoassay (CLIA) Kit is a Sandwich Chemiluminescent Immunoassay (CLIA) Kit for use with Serum, plasma, tissue homogenates, cell lysates and other biological fluids.


B-Cell Activating Factor (BAFF) CLIA Kit es un kit CLIA tipo Sandwich para su uso con suero, plasma, homogeinizados de tejido, lisados celulares y otros fluidos biológicos.


Background

TNFSF13B, commonly known as BAFF (B-cell activating factor), is a cytokine that belongs to the tumor necrosis factor (TNF) superfamily and is critical for B cell survival, maturation, and immune function. This ligand is primarily produced by myeloid cells, such as monocytes, macrophages, and dendritic cells, but can also be secreted by activated T cells. BAFF plays a pivotal role in maintaining peripheral B cell populations, supporting antibody production, and promoting immune tolerance. It interacts with specific receptors on B cells and related immune cells, including BAFF-R, TACI (Transmembrane Activator and Calcium-Modulating Cyclophilin Ligand Interactor), and BCMA (B Cell Maturation Antigen), to initiate intracellular signaling pathways crucial for B cell homeostasis and function. Dysregulation of BAFF expression or receptor binding is associated with autoimmune diseases, such as systemic lupus erythematosus (SLE), multiple sclerosis, and rheumatoid arthritis.

Características del producto

category

CLIA Kits


immunogen target

B-Cell-Activating Factor BAFF (BAFF)


reactivity

Chicken


test range

78 pg/ml - 5000 pg/ml


sensitivity

< 27 pg/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Chemiluminescent


sample type

Serum, plasma, tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


size 2

5 × 96 tests


size 3

10 × 96 tests


alias

Tumor necrosis factor ligand superfamily member 13B,DTL,BAFF,BLYS,CD257,TALL1,THANK,ZTNF4,TALL-1,TNLG7A,TNFSF20,B lymphocyte stimulator,BLyS,Dendritic cell-derived TNF-like molecule,TNF- and APOL-related leukocyte expressed ligand 1


storage

Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit


or code

TNFSF13B


dry ice

No


note

El rango y la sensibilidad pueden variar. Le recomendamos contactar con nosotros a fin de obtener la última información sobre posibles actualizaciones, que no estén representadas en este catalogo. Si necesita un rango específico, contáctenos y trataremos de ayudarle. Consulte sobre posible información que pueda ayudarle a elegir la dilución apropiada para sus muestras. Los kits CLIA están optimizados para la detección de muestras nativas, las proteínas recombinantes, pueden resultar problemáticas a causa de diferencias en la secuencia o cambios en la estructura terciaria.


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