Chicken Alpha Actinin 1 (ACTN1) Protein
234€ (10 µg)
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Name
Chicken Alpha Actinin 1 (ACTN1) Protein
Category
Proteins and Peptides
Provider
Abbexa
Reference
abx260638
Tested Applications
SDS-PAGE
Description
Alpha Actinin.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Proteins and Peptides |
| Immunogen Target | Alpha Actinin 1 (ACTN1) |
| Assay Type | Activity: Not tested |
| Origin | Chicken |
| Conjugation | Unconjugated |
| Purity | > 95% (SDS-PAGE) |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 1 mg |
| Form | Lyophilized |
| Tested Applications | SDS-PAGE |
| Availability | Shipped within 5-10 working days. |
| Dry Ice | No |
| UniProt ID | P05094 |
| Alias | BDPLT15 |
| Background | Protein ACTN1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
ACTN1 encodes alpha-actinin-1, a member of the actin-binding protein family that plays a key role in cytoskeletal organization and cellular architecture. It is primarily expressed in non-muscle cells, where it functions as a crosslinker of actin filaments and regulates the assembly of the actin cytoskeleton. ACTN1 is involved in diverse cellular processes such as cell adhesion, migration, and signaling, contributing to tissue integrity and dynamic cellular responses. It is also implicated in the regulation of focal adhesions and mechanotransduction. Mutations in ACTN1 have been associated with autosomal dominant macrothrombocytopenia, characterized by abnormally large platelets and reduced platelet count, highlighting its role in platelet formation and function. Its interaction with actin filaments and various signaling proteins underscores its importance in maintaining cellular stability and enabling dynamic cellular behaviors.
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